Groundbreaking weight loss drugs are coming to Costco pharmacies nationwide.

Novo Nordisk, the maker of Ozempic and Wegovy, announced Friday that Costco pharmacies will sell a four-week supply of the injectable pens for $499 out of pocket.

Without insurance, the cost can exceed $1,300, but through the manufacturer’s program, it can drop to $499, or even $0 to $25 for those with commercial insurance using a savings card, depending on their plan.

Manufacturers of effective weight loss drugs, including Novo Nordisk, are competing with compounding pharmacies and clinics that offer cheaper, generic-style versions of their blockbuster weight-loss drugs.

Roughly six percent of the US adults, or about 15.5 million people, were using one of these or a similar drug for weight loss as of early 2025.

While customers will still need a doctor’s prescription, the discounted price is significant because many insurance plans refuse to cover these medications.

While Ozempic and Wegovy both contain the drug semaglutide, they are approved for different conditions. Ozempic is FDA-approved to treat diabetes, and Wegovy is meant to treat obesity; they are dosed differently.

The new Costco partnership came partly from a desire to offer customers the ‘real, authentic’ medications where patients seek care, said David Moore, president of Novo Nordisk. ‘And we know that Costco is a trusted brand,’ he added.

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