đŸ”»The Bone Cost of Ozempic - Cypher News

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Rapid weight loss always takes something with it.

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Off-label use turns patients into data points.

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Risk warnings never move as fast as hype.

BRIEFING

Grant here. Over the last few years, weight loss medications like Ozempic, Mounjaro, and other GLP-1s have taken the world by storm. With a few shots into the body, people are able to easily drop the pounds, and it’s really so simple that it seems almost too good to be true. Well, unfortunately, it sort of is. A video is circulating that shows exactly what happens when a medical shortcut outruns the body’s biology. Let’s break it down.

The dangers surrounding GLP-1s come from a woman speaking on camera after a follow-up doctor’s visit, saying she had been on Ozempic for roughly a year and has now developed osteoporosis and osteopenia after significant weight loss on the drug.

As the video frames it, Ozempic is literally “eating women alive, one bone at a time.”

SOURCE

And this woman’s claims aren’t purely alarmist. There is documented evidence showing that GLP-1 weight loss drugs are linked to significant muscle loss and that rapid, drug-induced weight loss can carry real downstream consequences for bone health and metabolic stability.

In a major Ozempic trial, over 86% of participants lost at least 5% of their body weight, and nearly 70% lost 10% or more within 68 weeks. That level of loss matters, because speed like that has some serious effects on biology.

When weight drops quickly, muscle mass often drops with it. As lean muscle disappears, resting metabolic rate declines, physical strength weakens, and the body’s structural support system begins to shift. That entire process increases the risk of sarcopenia (the gradual loss of muscle mass and function), which is traditionally associated with aging but increasingly seen in younger patients undergoing aggressive weight loss.

SOURCE

“According to a clinical trial of Ozempic, after 68 weeks on the medication, 86.4% of participants lost 5% or more of their body weight, and 69.1% lost 10% or more of their body weight.”

While weight loss can bring about health benefits, losing weight rapidly can also cause a decrease in muscle mass, lessen bone density, and lower your resting metabolic rate, leading to sarcopenia â€” the gradual loss of muscle mass, strength, and function.

“Sarcopenia affects the elderly population and typically is associated with aging. However, rapidly losing weight with GLP-1s like Ozempic or Wegovy without the proper diet and exercise can also cause sarcopenia (sometimes referred to as ‘skinny fat’) at any age, negatively affecting a person’s quality of life by reducing their stamina and ability to perform daily activities, such as easily walking up stairs,” Dr. Rekha Kumar, a practicing endocrinologist in NYC and Chief Medical Officer of Found, told Healthline.

Sarcopenic obesity mimics obesity, she added, and occurs when a person’s BMITrusted Source is in the normal or low range, but their levels of lean muscle are so low that fat and bones are the only metabolically active tissue.

DEBRIEFING

Look, this video and the entire story here are not to label drugs like Ozempic as purely “bad,” but just to raise awareness of some of the real negative effects they can have in certain individuals. GLP-1 drugs don’t break the laws of biology, but they do clearly accelerate processes of weight loss, which is something the body normally experiences slowly. And speed is the variable no one is talking about enough, especially when it comes to overall bone health.

Clinical data shows just how aggressive GLP-1–driven weight loss can be. As we see in these major Ozempic trials, most participants lost significant amounts of weight in under a year, and that pace often strips away lean muscle along with fat, which inevitably leads to
 ding, ding: bone loss. 

So no, this isn’t purely a story about a drug “eating women alive.” That framing is perhaps a bit too emotional, but still, it’s not entirely unproven either.

But what’s really real here is the lag. Meaning, the enthusiasm around GLP-1s moved faster than the warnings. Remember, these drugs were originally intended for those with diabetes, and “off-label use” was normalized before most people understood the long-term tradeoffs of rapid, pharmacological weight loss.

At the end of the day, human biology has a way of catching up sooner or later. The bill is coming due from these GLP-1s through follow-up appointments, bone scans, and the real-life complications that didn’t make the shiny commercial ads.

NOW YOU KNOW

When weight falls quickly, something else gives.