New York has always had the hottest real estate.

Buildings dating back to the earliest days of the Big Apple are sprinkled across the five boroughs — standing as living reminders of nearly four centuries of city history.

These ancient edifices include stately manors, humble farmhouses and one of New York’s earliest nightlife spots — each of which survived the Revolutionary War and lasted to see America’s 250th birthday.

Here’s a list of the oldest structures still standing in every borough:

Wyckoff House, Brooklyn

Brooklyn boasts the oldest building in the five boroughs — the Wyckoff House, built circa 1652.

The farmhouse on Clarendon Road was constructed by Pieter Claesen Wyckoff, who became a successful farmer and magistrate after serving an indenture for the van Rensselaer family.

Wyckoff was influential in establishing the still-standing Flatlands Dutch Reformed Church at the juncture of Flatbush Avenue and Kings Highway.

Generations of Wyckoffs enlarged and altered the House and continued to farm the land until 1901, and the property became the first structure to be designated a New York City Landmark in 1965.

“Its history exemplifies the diversity of Brooklyn’s colonial farms, where Dutch-American landowners, enslaved and freed Africans, and later European immigrants labored on some of the country’s most fertile land,” according to the Parks Department, which owns the property.

Today, the building it open to the public as the Wyckoff House Museum.

Bowne House, Queens

The Bowne House played a pivotal role in establishing religious tolerance in the US.

Standing on its eponymous street in Flushing since 1661 — the humble home built by John Bowne, who emigrated from England while New York was under Dutch rule.

Bowne hosted Quaker meetings in his house — and was arrested by Peter Stuyvesant, Dutch Director-General of New Netherland, for knowingly defying the state religion of the Dutch Reformed Church.

The farmer successfully appealed the arrest to the Dutch West India Company — laying the precedent for Constitutional religious freedom, speech and the right of assembly.

Bownes lived in the wood-frame Anglo-Dutch Colonial saltbox until 1945, when they bestowed it onto the Bowne House Historical Society.

Today, it is open to the public as a museum — and even displays a chair George Fox, one of the founders of Quakerism, sat in during a visit that hasn’t been moved in more than 250 years.

Billiou–Stillwell–Perine House, Staten Island

The Billliou-Stillwell-Perine House in Dongan Hills is considered the “oldest surviving building” in Richmond County, according to the borough’s historic society.

The oldest section of the home was built in 1663 by Pierre Billiou, a native of French Flanders who arrived with a group of settlers who established Staten Island’s first European settlement.

His daughter inherited the house along with her husband, Thomas Stillwell, who served in the English political system during the colonial period as Constable, Sheriff, Magistrate, and Member of the Colonial Assembly.

Several families occupied the fieldstone and wood-framed home in the following decades, including the Brittons, Dongans, Holmes, and Perines.

The property was purchased by the Staten Island Antiquarian Society in 1915 to preserve its history as a museum.

Fraunces Tavern, Manhattan

Perhaps the most famous, Fraunces Tavern made history as the epicenter of Patriot activity during the Revolutionary War — and continues to serve cold ones today.

The building was originally built by the De Lancey family in 1719 as a private home, but was turned into a tavern in 1762 by Samuel Fraunces.

The Pearl Street pub was a popular meeting spot for the rebel spies, Founding Fathers and New York Sons of Liberty, including George Washington, Samuel Adams, John Hancock, John Jay, Henry Knox, Paul Revere and Benjamin Tallmadge during the British occupation of the Big Apple.

Alexander Hamilton and Aaron Burr dined together at the Tavern one week before their infamous duel, and Washington hosted a celebration at the pub on Evacuation Day in 1783.

The building has gone through several renovations, but the original bones are still intact and thousands of artifacts from its history remain inside.

While it has a museum inside, Fraunces Tavern continues to operate as a bar and restaurant.

Van Cortlandt House, the Bronx

The Van Cortlandt House is the centerpiece of the 1,000-acre park of the same name that encompasses what was once the Van Cortlandt family’s plantation.

Jacobus Van Cortlandt — a wealthy New Amsterdam-born merchant and two-time Big Apple mayor — bought the sprawling property in 1694, but it wouldn’t be until 1748 that his son, Frederick, built the current house, according to its namesake museum.

The house was on contested grounds during the Revolutionary War, with the British and the rebels at different times ruling the not-yet-named borough — though General Washington stayed at the house in 1776 and 1783.

While the former acres of wheat, rye and corn have been transformed into modern-day athletic fields, the marks of the African slaves the Van Cortlandt family kept. Several of the still-maintained park trails and the dammed Tibbetts Brook were created by the slaves.

Van Cortlandt descendants lived in the House until 1886, when they sold the entire estate to the City of New York for Van Cortlandt Park.

Today, it serves as a museum.